Evgeny M. TIMANIN

Institute of Applied Physics
46 Uljanov str.
Nizhny Novgorod 603950
Russia
Phone: (+7-8312) 164-986
Email:
eugene@appl.sci-nnov.ru

 

Qualifications:

  • Dip.Ed., Gorky (Nizhny Novgorod) State University, radiophysics, 1977 .
  • Ph.D., Institute of Theoretical and Experimental Biophysics Russian Academy of Sciences, Pushchino, Russia, biophysics (physics and mathematics), 1992 .

Professional Experience:

  • Institute of Applied Physics, Russian Academy of Sciences, Senior Research Scientist - Appointed: 1995
  • IAP RAS, division of Radiophysical Methods in Medicine, Assistant Head - Appointed: 1993
  • 1989, Research Scientist, IAP RAS, division of Radiophysical Methods in Medicine
  • 1982, Junior Research Scientist, IAP RAS, division of Radiophysical Methods in Medicine
  • 1979, Engineer, IAP RAS, division of Radiophysical Methods in Medicine
  • 1977, Research Trainee, IAP RAS, division of Radiophysical Methods in Medicine

Expertise and Research Interests:

The general direction of my research work in biomechanics is investigation of muscle viscoelastic characteristics. Before 1986 some works had been performed on modeling of the mechanism of muscle contraction as well on modeling of viscoelastic properties of active muscle samples. Later, the main focus of work was replaced on the viscoelastic properties of human muscles in situ. Their experimental studies had been accomplished on the basis of mechanical impedance measurements as well as a simple model of soft tissues mechanical impedance had been offered. More realistic models of mechanical impedance of layered tissues have been developed not so long ago, as well the models of low-frequency vibrations excitation within layered tissues by a surface source (for sonoelastography method).
In parallel with the above-described work some works in biomedical engineering were led. The main direction of these works is vibroacoustical equipment development for human muscle disorders (or neuromuscular disorders) diagnostics and treatment evaluation. All the devices are based on noninvasive evaluation of the muscle viscoelastic characteristics by means of mechanical impedance measurements. There are two types of devices. The first one provides to measure the frequency dependencies of mechanical impedance, the second one provides to measure the
temporal dynamics of mechanical impedance with resolution from 0.1s to 0.001s. Evolution of the technique from autonomous devices to hardware-software complexes operating under MS DOS and Windows 95/98 was gone.

Other Expertise:

Viscoelastic and nonlinear properties investigation of complicated materials such as polymers, porous and grainy media.

Keywords:

Mechanical impedance; sonoelastography; muscle elasticity and viscosity in situ; impedance myography; motor control; diagnostics and treatment evaluation; muscle disorders; neuromuscular disorders; human tissue.

Future Research:

  • Biomedical engineering: Computer-assisted systems design for muscle disorders (or neuromuscular disorders) diagnostics and treatment evaluation, as well as their clinical trial.
  • Biomechanical research: Experimental study of muscle elasticity and viscosity in situ and investigation of the mechanisms of motor control on this basis.

Publications:

  1. Timanin EM, Eremin EV, Interpretation of Impedance Characteristics of Biological Soft Tissues in the Models with a Pressure Source of Vibrations with Friction // Proceedings of the XIII Session of the Russian Acoustical Society. V.3. Speech acoustics. Medical and biological acoustics. Moscow: GEOS, 2003, P.175-179.
  2. Timanin E.M., Eremin E.V. Interpretation of Mechanical Impedance of Biological Tissues in the Three-Layered Model with the Pressure Source of Vibrations // Biophysics, 2003, 48(2), P.324-331.
  3. Timanin E.M., Eremin E.V. Ultrasonic Doppler Imaging of Nonlinear Elastic Shear Properties of Biological Tissue Phantoms // Nonlinear Acoustics at the Beginning of the 21-st Century / Edited by O.V.Rudenko and O.A.Sapozhnikov. Moscow: Faculty of Physics, MSU, 2002. V.1. P.449-452.
  4. Timanin E.M., Eremin E.V. Monitoring of Biceps Characteristics in Sustained Isometric Contractions by the Methods of Impedance Mechanomyography and Electromyography // Acta of Bioengineering and Biomechanics. 2002. V. 4, Suppl. 1 / Proceedings of the 13-th Conference of European Society of Biomechanics. Wroclaw, 2002. P.616-617.
  5. Timanin E.M., Eremin E.V. Availability check of methods of computer-assisted impedance mechanomygraphy // Modern Information Technologies in Diagnostic Findings. Proceedings of the International Conference. Dnipropetrovsk: Porogi, 2002, P.191-194.
  6. Timanin E.M., Eremin E.V. Ultrasonic Doppler visualization of induced vibration shifts in biotissue phantoms // Methods of acoustic diagnostics of inhomogeneous media. Collected Papers. Nizhny Novgorod: IAP RAS, 2002, P.247-258.
  7. Timanin E.M., Eremin E.V. Ultrasonic Doppler Imaging of Nonlinear Elastic Shear Properties of Biological Tissue Phantoms // 16th International Symposium on Nonlinear Acoustics. Abstracts. – Moscow, 2002. P.137.
  8. Timanin E.M. Displacement Field Produced by a Surface Source of Vibrations in a Layered Biological Tissue // Acoustical Physics, 2002, 48(1), P.87-93.
  9. Eremin EV, Timanin EM, Pilot experiments on ultrasonic registration of amplitudes and phases of vibrations in the phantom of biological tissue // Proceedings of the XI Session of the Russian Acoustical Society (Moscow, November 19-23, 2001). V.3. Speech acoustics. Medical and biological acoustics. Moscow: GEOS, 2001, P.191-194.
  10. Timanin E.M. Models of vibrations generation within biological tissue by a surface source // Proceedings of the XI Session of the Russian Acoustical Society (Moscow, November 19-23, 2001). V.3. Speech acoustics. Medical and biological acoustics. Moscow: GEOS, 2001, P.195-198.
  11. Timanin E.M. Models of vibrations generation within biological tissue by a surface source // 17-th International Congress on Acoustics. Book of abstracts. Rome, 2001. P.212.
  12. Timanin EM, Eremin EV, Alterations of biceps mechanical and electromyographic characteristics during its isometric contraction. Pre-print IAP RAS N 554, Nizhny Novgorod, 2001, P. 1-21.
  13. Eremin EV, Timanin EM, Software-hardware complex for studying the the temporal dynamics of impedance characteristics of biological soft tissues // Nizhny Novgorod session of young scientists VI. Abstracts collection. Nizhny Novgorod, 2001. P. 67.
  14. Eremin EV, Timanin EM, Software-hardware complex for spectra registration of mechanical impedance of biological soft tissues // Nizhny Novgorod session of young scientists V. Abstracts collection. Nizhny Novgorod, 2000. P. 42-43.
  15. Eremin EV, Timanin EM, Automated reconstruction of elasticity and viscosity modules of gelatine layer from the mechanical impedance measurements // Abstracts of the 5-th All-Russia conference on biomechanics "Biomechanics - 2000", Nizhny Novgorod, May 29 - June 2, Nizhny Novgorod: IAP RAS, 2000, p. 40.
  16. Eremin EV, Timanin EM, Interpretation of a Layer Mechanical Impedance Measured Using a Hard Round Die // Acoustical Physics, 2000, 46(4), p. 421-426.
  17. Timanin EM, Eremin EV, Mechanichal Impedance of Biological Soft Tissues: Possible Models. Russian Journal of Biomechanics, 1999, V.3. N 4, p. 78-86. (Full PDF-text, 335 kB)
  18. Timanin EM, On the possible models of impedance characteristics of biological soft tissues, Russian Journal of Biomechanics, 1999, N 2, p.125-126.
  19. Timanin EM, On the possibilities of impedance characteristics description of biological soft tissues in the models with the pressure source of vibration, Pre-print IAP RAS N 488, Nizhny Novgorod, 1999, p. 1-32.
  20. Timanin EM, Reyman AM, Eremin EV, Software-hardware complexes for studying the impedance characteristics of biological soft tissues, Abstracts of the "2-nd Congress of biophysicists of Russia", Moscow, 23-27 Aug., 1999, v.2, p. 626-627,
  21. Timanin EM, Possibilities of myotonography, Meditsinskaia Tekhnika (Biomedical Engineering), 1998, N 2, p. 39-41.
  22. Timanin EM, A review of the possibilities of the impedance myography method, Abstracts of the 4-th All-Russia conference on biomechanics "Biomechanics - 98", Nizhny Novgorod, 1-5 June, 1998, p. 85.
  23. Timanin EM, Reyman AM, Singosina TB, Study of the response of some limb muscles to the load on the basis of measurement of their viscoelastic characteristics, Abstracts of the "3-d All-Russia conference on biomechanics", Nizhny Novgorod, 1-4 Oct., 1996, v. 1, p. 174-175.
  24. Timanin EM, Shalagina NV, On the possibilities of study of knee reflex on the basis of measurements of viscoelastic characteristics of m. quadriceps femoris, Abstracts of the "3-d All-Russia conference on biomechanics", Nizhny Novgorod, 1-4 Oct., 1996, v. 1, p. 176-177.
  25. Anishkina NM, Antonets VA, Mansfeld AD, Reyman AM, Kazakov VV, Timanin EM, Babikov DB, Kirillov AG, Ksenofontov SYu, Shishkov AV, The computer-based tools to evaluate the functional state of human organism (locomotive and cardiovascular systems), Abstracts of the "3-d All-Russia conference on biomechanics", Nizhny Novgorod, 1-4 Oct., 1996, v. 1, p. 197-198.
  26. Mansfeld AD, Timanin EM, On the possibility of through measurements of shear viscoelastic parameters of biological tissues, Akusticheskii Zhurnal (Acoustical Physics), 1995, 41(3), p. 514-515.
  27. Klochkov BN, Timanin EM, Nonlinear effects in oscillation of an indentor on the surface of soft tissues, Acoustical Physics, 1994, 40(6), p. 844-847.
  28. Belyaeva IYu, Zaitsev VYu, Timanin EM, Experimental study of nonlinear elastic properties of granular media with nonideal packing, Acoustical Physics, 1994, 40(6), p.789-793.
  29. Timanin EM, Shevchenko OV, On the possibilities of evaluation of vibration influence on the human forearm by measuring the muscles viscoelastic characteristics, Abstracts of the "2-nd All-Russia conference on biomechanics", Nizhny Novgorod, 22-25 Nov., 1994, v. 2, p. 96-97.
  30. Glushkov EV, Glushkova NV, Timanin EM, Determination of the impedance and wawe-guide properties of biological-materials, Acoustical Physics, 1993, 39(6), p. 551-553.
  31. Timanin EM, Spivak-Baranov ME, Filonenko SB, Study of viscoelastic characteristics of skeletal muscles during electrical stimulation, Abstracts of the 1-st All-Russia Conference-Fair "Biomechanics on the protection of human life and health", Nizhny Novgorod, 1992, 9-12 Nov., v. 2, p. 240.
  32. Belyaeva IYu, Ostrovsky LA, Timanin EM, Experiments on harmonic generation in grainy media, Acoustics Letters, 1992, 15(11), p. 221-224.
  33. Belyaeva IYu, Timanin EM, Experimental-study of the nonlinear properties of porous elastic media, Acoustical Physics, 1991, 37(5), p. 533-534.
  34. Timanin EM, Experimental studies and modeling of impedance properties of biological soft tissues, Abstracts of the "11-th All-Union acoustical conference", Moscow, 24-28 June, 1991, Section O, p.48-50.
  35. Timanin EM, On the nature of contact mechanical impedance of soft biological tissue Abstracts of the International symposium "Mechanisms of acoustical bioeffects", Pushchino, 14-18 May, 1990, p. 70.
  36. Timanin EM, A model of formation of impedance properties of soft biological tissues. In: "Methods of vibrational diagnostics of rheological properties of soft materials and biological tissues", IAP RAS, Gorky, 1989, p. 75-91.
  37. Rozenblum LA, Ovchinnikov EYu, Timanin EM, Antonets VA, Gorelov YuL, Determination method of viscoelastic properties of polymers, Plasticheskie massi (Plastics), 1989, N 12, p. 74-76.
  38. Timanin EM, Prospects for measuring the rheologic characteristics of human soft tissues based on the recording of their transverse rigidity, Biofizika (Biophysics), 1989, 34(3), p. 512-516.
  39. Timanin EM, On contribution of shear waves into a transverse stiffness of soft biological tissues in vibrating indentor investigations, Abstracts of the "13-th International Congress on Acoustics", Belgrade, 24-31 Aug., 1989, v. 4, p. 215-218.
  40. Timanin EM, The set of laboratory equipment for measuring viscoelastic properties of biological soft tissues by the method of vibrating indentor, Abstracts of the 9-th All-Union conference "Measurements in medicine and their metrology", Moscow, 5-9 June, 1989, p. 158.
  41. Timanin EM, Experimental study of rheological characteristics of the human forearm muscle on the basis of registration of its dynamic transverse stiffness, Abstracts of the 8-th All-Union symposium "Biophysics and biochemistry of biological motility. Pushchino, 16-18 Nov. 1987", Tbilisi, 1987, p. 118.
  42. Timanin EM, The molecular interpretation of the rheological model of muscle tissue and its using for the muscle contraction study, Biofizika (Biophysics), 1986, 31(2), p. 366.
  43. Timanin EM, Rheological model of muscle tissue in a state of constant activation, Biofizika (Biophysics), 1984, 29(3), p. 135-138.
  44. Timanin EM, A macroscopic description of stress relaxation in a muscle subject to stepwise deformation, Biorheology, 1984, 21(6), p. 799-808.
  45. Timanin EM. Modified kinetic model of muscle contraction, Biofizika (Biophysics), 1981, 26(5), p. 915-916.
  46. Timanin EM, Antonets VA, Theoretical analysis of possible construction of biomechanical parameters of energy expenditures in heart muscle, Biofizika (Biophysics), 1981, 26(3), p. 507-511.

Patent Information:

  1. Patent 2082312 Russia, The device for determination of viscoelastic characteristics of soft tissues, Timanin EM, Antonets VA, Shishkov AV, Dmitriev GI, Dmitriev DG, Zhegalov VA, 1997.
  2. Patent 1548750 USSR, The method for determination of an elasticity dynamic modulus and a corner of mechanical losses, Rozenblum LA, Antonets VA, Timanin EM, Ovchinnikov EYu, 1990.

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